Medical Materials MCC PH103 CAS 9004-34-6 In Pharmaceutic Preparation

Medical Materials MCC PH103 CAS 9004-34-6 in Pharmaceutic Preparation

Basic Information Form of Medical Materials MCC PH103 CAS 9004-34-6

What is Medical Materials MCC PH103 CAS 9004-34-6 in Pharmaceutic Preparation?

Microcrystalline Cellulose (MCC PH103) powdered cellulose products are used as high-grade plant fillers and standard binders for tablets. Powdered cellulose products (microcrystalline cellulose) binder excipients are a high-quality, high-grade, ultra-refined product range optimized for modern tablet production. They provide convincing results in all tablet compression processes, capsule filling as well as suspension and emulsion production.

Microcrystalline cellulose (C6H10O5)n is a refined wood pulp. It is a free-flowing white powder. Chemically, it is an inert substance that does not degrade during digestion and has no significant absorption capacity. Ingestion of large quantities increases dietary bulk and has a laxative effect.

Microcrystalline cellulose is a commonly used excipient in the pharmaceutical industry. It has excellent compressibility and can be used in solid dosage forms such as tablets. Hard but rapidly dissolving tablets can be made. Microcrystalline cellulose is the same as cellulose, but it meets U.S. Pharmacopeia standards.

It is also found in many processed foods and can be used as an anti-caking agent, stabilizer, texture modifier, or suspending agent. According to the GRAS Substance Selection Committee, microcrystalline cellulose is generally considered safe at normal dosages.

Uses of (Medical Materials MCC PH103 CAS 9004-34-6 in Pharmaceutic Preparation

Fillers: Fillers are necessary in the production of tablets with very low drug doses. Microcrystalline cellulose can be used in all types of tablet manufacturing processes such as direct compression, wet granulation, and dry processing.

Direct Compression: MCC can be used as an excipient for direct compression tablets. It has high dilution capacity and high active ingredient carrier capacity. It maintains its integrity even during direct compression. Another reason for its popularity is its low bulk density and therefore high dilution and packaging density. It helps to produce harder tablets that are less prone to breakage. In addition, it provides excellent whiteness and stability.

Wet Granulation: As mentioned earlier, it is both insoluble and hydrophilic. Therefore, it is the preferred choice for this manufacturing process. The advantage of using MCC is that it retains moisture and helps in uniform granulation. Shell coagulation is a process used for inadequately dried granules. When pellets are dried at high temperatures, the inside of the pellet also remains wet and the surface appears to be dry. MCC is useful because it is less sensitive to wet mass and therefore does not over-wet, dries faster, less hardening is observed, and breaks down very quickly.

Roll Compaction: Roll compaction is a dry process that involves compacting the material into strips that are then processed to form pellets. The granules are then coated with grease and packaged in a tablet machine. The use of MCC in this process improves compaction, flow, and content uniformity.

Binders: Binders are very useful in order to obtain proper mechanical strength and giving volume to smaller doses of active ingredients. It affects the quality and appearance of the tablet. Considering the water absorption of MCC, it is widely used as a binder in the pharmaceutical industry.

Disintegrants: MCC is widely used as a disintegrant in dry tableting and wet granulation systems. It improves the disintegration of sedatives by accelerating the disintegration of tablets, provides maximum disintegration force at low dosage levels, and utilizes dual disintegration by water absorption and swelling to achieve faster disintegration.

Since its introduction, MCC has revolutionized pharmaceutical research, bringing assembly efficiency to a whole new level.

Packaging and Storage of Medical Materials MCC PH103 CAS 9004-34-6 in Pharmaceutic Preparation

Packaging: 1kg/bag, 25kg/paper drum, or as per your requirement.
Storage: Hermetically sealed, protected from light, in a dry place. Avoid direct sunlight.

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