Product Details
Place of Origin: China
Brand Name: Hongbaiyi
Certification: COA, HPLC MR
Model Number: HBY-GLP-3
Document: Product Brochure PDF
Payment & Shipping Terms
Minimum Order Quantity: 5boxes
Packaging Details: 40mg, 50mg, 60mg
Delivery Time: 3-5 work days after your payment
Payment Terms: T/T
Supply Ability: 20000 boxes/month
Name: |
(GLP-3 RT) |
Appearance: |
Lyophilized Powder |
CAS Number: |
2381089-83-2 |
Specification: |
40/50/60mg/ Vial |
Lyophilized (powder): |
−20 °C Stable |
Purity: |
99% Pure |
Other Name: |
LY3437943 |
Name: |
(GLP-3 RT) |
Appearance: |
Lyophilized Powder |
CAS Number: |
2381089-83-2 |
Specification: |
40/50/60mg/ Vial |
Lyophilized (powder): |
−20 °C Stable |
Purity: |
99% Pure |
Other Name: |
LY3437943 |
Overview
Reta (also known as GLP-3 or RT) is a 39-amino acid peptide whose main chain is based on glucagon and has been modified so that a single molecule can simultaneously activate the GLP-1, GIP, and glucagon receptors. Non-coding residues at positions 2, 13, and 20 contribute to increased stability and receptor balance, while the C20 fatty acid chain enables binding to albumin, thereby prolonging the half-life.
This compound is prepared via solid-phase synthesis and preparative purification, and is subsequently released with a batch-matched certificate of analysis (including HPLC purity and LC-MS identification data).
Research Applications
Researchers use Reta to investigate how glucagon receptor activity acts on incretin signaling pathways that GLP-1 (Sema) and GLP-2 (Tirz) cannot activate. Typical studies include cAMP reporter assays targeting GCGR, GIPR, and GLP-1R in HEK293 cells; models of hepatic lipid metabolism and thermogenesis; and rodent studies measuring the relationship between energy expenditure and food intake.
