Mazdutide (IBI-362 / LY-3305677) 5mg GLP-1R And Glucagon Receptor Agonist

Product Overview:

Dihexa is a small synthetic peptide-like research compound with the CAS number 1401708-83-5. It is primarily studied in neuroscience research for its potential role in promoting neurotrophic activity and supporting synaptic growth pathways. As a highly potent experimental molecule, Dihexa has been investigated in preclinical settings for its interaction with hepatocyte growth factor (HGF) signaling pathways, which are associated with neural repair and cognitive function mechanisms.

This product is intended strictly for laboratory research purposes only and is not approved for human consumption, medical use, or veterinary application. It is supplied as a 10 mg quantity, suitable for controlled experimental and analytical studies in research environments.

• CAS Number: 1401708-83-5
• Purity: Research grade (typically ≥98%)
• Form: Lyophilized powder
• Quantity: 10mg per vial
• Application: Scientific research in neuroscience and related fields

1. Active Substance:
Mazdutide (also known as IBI-362 / LY-3305677)

2. Dosage Strength:
5 mg per vial

3. Drug Class / Type:
Long-acting synthetic peptide
Dual agonist of:

• GLP-1 receptor (GLP-1R)
• Glucagon receptor (GCGR)

4. Mechanism of Action:
Mazdutide simultaneously activates GLP-1R and GCGR, which may influence:

• Glucose metabolism regulation
• Appetite signaling pathways
• Energy expenditure pathways
• Lipid metabolism modulation

5. Physical Form:

• Typically white to off-white lyophilized powder
• Requires reconstitution before use (commonly with sterile water or bacteriostatic water in research settings)

6. Molecular Characteristics:

• Engineered long-acting peptide analog
• Modified structure to increase receptor stability and half-life
• High binding affinity to both GLP-1R and GCGR

7. Solubility:

• Water-soluble after reconstitution
• Stable under refrigerated conditions (typically 2–8°C after preparation, depending on formulation)

8. Storage Conditions:

• Unreconstituted: -20°C (recommended long-term storage)
• Reconstituted: 2–8°C, avoid freezing and repeated freeze-thaw cycles

9. Research Use Status:

• Investigational compound (not approved as a finished pharmaceutical product in most markets)
• Used in metabolic and endocrinology research